标题: Effects of moxifloxacin and gatifloxacin stress on growth, photosynthesis, antioxidant responses, and microcystin release in Microcystis aeruginosa

作者: Wan, L (Wan, Liang); Wu, YX (Wu, Yixiao); Zhang, BH (Zhang, Benhao); Yang, WF (Yang, Wenfeng); Ding, HJ (Ding, Huijun); Zhang, WH (Zhang, Weihao)

来源出版物: JOURNAL OF HAZARDOUS MATERIALS  卷: 409  文献号: 124518  DOI: 10.1016/j.jhazmat.2020.124518  出版年: MAY 5 2021  

摘要: Moxifloxacin (MOX) and gatifloxacin (GAT) are fourth-generation fluoroquinolone antibiotics that are frequently detected in surface water environments and pose a threat to aquatic organisms. However, research into their toxicity to Microcystis aeruginosa, a cyanobacterium, has thus far been limited. In the present study, we investigated the effects of these antibiotics on M. aeruginosa growth, photosynthesis, oxidative stress, and microcystin (MC) release. The results of the 96 h EC50 values of MOX and GAT were 60.34 and 25.30 mu g/L, respectively, and the risk quotients calculated indicated that these antibiotics could pose considerable ecological risks at actual environmental concentrations. Photosynthetic fluorescence intensity was shown to decline markedly, and Fv/Fm significantly decreased without any evidence of recovery, suggesting that the organism's photosystems were irreversibly damaged. Chlorophyll a and camtenoid content decreased, whereas the ratio of camtenoids to chlorophyll a increased, indicating that camtenoids were less susceptible to damage than chlorophyll a. The reactive oxygen species and malondialdehyde content significantly increased, as well as the superoxide dismutase and catalase activities, indicating that exposure caused serious oxidative stress. Additionally, MC release increased. These results demonstrate that the environmental risks posed by MOX and GAT should be given serious consideration, particularly as their use is increasing.

入藏号: WOS:000621669800002

语言: English

文献类型: Article

作者关键词: Toxicity; Fluoroquinolones antibiotics; Cyanobacteria; Oxidative damage

地址: [Wan, Liang; Wu, Yixiao; Zhang, Benhao; Yang, Wenfeng; Zhang, Weihao] Wuhan Univ, Sch Resource & Environm Sci, Wuhan 430079, Peoples R China.

[Zhang, Weihao] Wuhan Univ, Sch Resource & Environm Sci, Hubei Biomass Resource Chem & Environm Biotechnol, Wuhan 430079, Peoples R China.

[Ding, Huijun] Jiangxi Prov Inst Water Sci, Jiangxi Prov Key Lab Water Resources & Environm P, Nanchang 330029, Jiangxi, Peoples R China.

通讯作者地址: Zhang, WH (通讯作者)，Wuhan Univ, Sch Resource & Environm Sci, Wuhan 430079, Peoples R China.

电子邮件地址: zhangwh@whu.edu.cn

影响因子：9.038